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Medical clearance ensures all concussion symptoms have completely resolved, and brain function has returned to pre-injury levels

doi: 10.1111/jth.14234 Summary Keywords trimethylamine N-oxide, atherosclerosis, cardiovascular disease, inflammation mechanism, clinical prognostic stratification, therapy Citation Yang S, Li X, Yang F, Zhao R, Pan X, Liang J, Tian L, Li X, Liu L, Xing Y and Wu M (2019) Gut Microbiota-Dependent Marker TMAO in Promoting Cardiovascular Disease: Inflammation Mechanism, Clinical Prognostic, and Potential as a Therapeutic Target

hazard ratios 1.54-1.95) Masseter domain patients saw their mean duration fall from ~20.1 2.9 weeks in controls to 17.3, 17.0, 16.7 and 16.2 weeks (hazard ratios 1.72-2.08) Sensitivity analysis suggested ~55% of the reduction in duration was attributable to synaptic modulation, ~30% to lean-mass decline, and ~15% to metabolic variability

Hui, H., Farilla, L., Merkel, P., & Perfetti, R